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KMID : 0948220150190030071
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Keimyung Journal of Nursing Science
2015 Volume.19 No. 3 p.71 ~ p.79
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Mechanism of Weight Gain in Kidney Transplantation Recipients
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Cho Young-Eun
Cashion Ann
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Abstract
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Purpose: Weight gain after kidney transplantation is one of the common complications, which might lead to co-morbid conditions including hypertension and diabetes. It is closely related to early graft loss, unfavorable long-term outcomes and poor survival rate. In this paper, we discussed various factors which might induce weight gain after kidney transplant.
Methods: The impact of demographic factors, immunosuppressants, nutrition and physical activity, psychosocial factors and genomic factors in weight gain after kidney transplant is reviewed.
Results: Factors related to weight gain post-transplant include demographic features (race and gender), immunosuppressants, unbalanced nutrition intake and decreased physical activity, depression and low socioeconomic status, and highly expressed obesity-related genes. However, study results vary depending on the characteristics of the study population, duration of the observation post-transplant and analysis method.
Conclusion: Many factors related to weight gain after kidney transplant are modifiable. Therefore, prior to transplantation and during the post-transplant period, clinicians should consider all these factors to provide appropriate interventions to prevent weight gain.
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KEYWORD
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Kidney Transplantation , Weight Gain , Immunosuppressants , Nutrition , Psychosocial Factors , Gene Expression
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